Alkyl Polyglycosides i nā huahana mālama pilikino

I loko o nā makahiki he ʻumi i hala iho nei, ua holomua ka hoʻomohala ʻana i nā mea maka no nā huahana mālama pilikino i ʻekolu mau wahi nui:

（1） ʻoluʻolu a mālama i ka ʻili

（2） nā kūlana kiʻekiʻe ma o ka hoʻemi ʻana i nā huahana a me ka ʻike ʻana i nā haumia

（3） kaiaola.

Ke hoʻoikaika nui nei nā lula kūhelu a me nā pono o nā mea kūʻai aku i nā hoʻomohala hou e hahai ana i nā loina o ke kaʻina hana a me ka hoʻomau ʻana o ka huahana. ʻO kekahi hiʻohiʻona o kēia kumumanaʻo ʻo ia ka hana ʻana i nā alkyl glycosides mai nā aila meaʻai a me nā haʻahaʻa mai ke kumu hou. Pono ka hoʻomohala ʻana o ka ʻenehana kalepa i kahi kiʻekiʻe kiʻekiʻe o ka mana ma luna o nā mea maka, nā hopena a me nā kūlana hana e hoʻokō ai i nā koi o ka pono o nā mea hoʻonaninani hou a hana iā lākou ma ke kumu kūʻai kūpono. Ma ke kahua o ka cosmetics, alkyl glucoside he ʻano hou o ka surfactant me nā waiwai non-ionic a me nā anionic. I kēia lā, ʻo ka hapa nui o nā huahana ʻoihana nā mea hoʻomaʻemaʻe i hōʻike ʻia e C8-14 alkyl glycosides, i hōʻike ʻia e ko lākou ʻili a me nā hiʻohiʻona mālama lauoho. Hana ʻo C12-14 alkyl polyglycoside ma ke ʻano he emulsifier i nā ʻano kikoʻī a me nā microemulsions a me ke aʻo ʻana i ka hana ʻana o C16-18 alkyl polyglycoside ma ke ʻano he emulsifying o/w base i hui pū ʻia me ka waiʻona momona.

No ka hoʻomaʻemaʻe kino kino, pono e loaʻa i kahi surfactant hou o kēia manawa ke kūpono maikaʻi me ka ʻili a me nā membrane mucous. Pono nā ho'āʻo dermatological a me toxicological e loiloi i ka hopena o kahi surfactant hou a me ka hoʻolālā ʻana i ka mea nui loa e ʻike i ka hiki ke hoʻoulu ʻia o nā mea ola i ka papa basal epidermal. I ka wā ma mua, ʻo ia ke kumu o nā ʻōlelo haʻahaʻa surfactant. I ka manawa like, ua loli nui ka manaʻo o ke akahai.

Ma o nā ʻano dermatological a me biophysical like ʻole, ua aʻo ʻia nā hopena physiological o nā surfactants ma ka ʻili, e hoʻomaka ana mai ka ʻili o ka ʻili a piʻi i ka hohonu hohonu o nā cell basal ma o ka stratum corneum a me kāna hana pale. , e like me ke ʻano o ka ʻili, hoʻopaʻa ʻia ma o ka ʻōlelo o ka pā a me ka ʻike.

ʻO nā polyglycosides alkyl me nā kaulahao alkyl C8 a i ka C16 no ka hui o nā surfactants māmā loa no ka hoʻomaʻemaʻe kino. Ma kahi noiʻi kikoʻī, ua wehewehe ʻia ka hoʻohālikelike o nā polyglycosides alkyl ma ke ʻano he hana o ke kaulahao alkyl maʻemaʻe a me ke degere o ka polymerization. ʻO C10 a me C14, C16 alkyl polyglycoside e hana i nā helu hoʻonāukiuki haʻahaʻa. Pili kēia i nā ʻike me nā papa ʻē aʻe o nā surfactants. Eia kekahi, e emi iki ka huhū me ka piʻi ʻana o ka polymerization (mai DP= 1.2 a i DP= 1.65).

ʻO nā huahana APG me ka lōʻihi o ke kaulahao alkyl i hui pū ʻia, ʻoi aku ka maikaʻi o ka hoʻohālikelike ʻana me ka hapa kiʻekiʻe o nā alkyl glycosides lōʻihi (C12-14). - nā ʻakika momona ma ka collagen a i ʻole nā ​​mea proteolytic palaoa.

Hōʻike nā ʻike dermatological i ka hoʻāʻo holoi holoi lima i ka pae like me ka Duhring Chamber Test i hoʻololi ʻia kahi e noiʻi ʻia ai nā ʻōnaehana hui ʻana o ka alkyl ether sulfate a me alkyl polyglycosides a i ʻole amphoteric co-surfactants. Eia nō naʻe, ʻo ka hoʻāʻo ʻana i ka holoi lima lima hiki ke hoʻokaʻawale maikaʻi i nā hopena. Hiki ke ho'emi 'ia ka ho'okumu 'ana o ka erythema a me ka squamation e 20-30 D/o inā ma kahi o 25 °10 o SLES e pani 'ia e ka alkyl polyglycoside e hō'ike ana i ka emi 'ana ma kahi o 60 %. I ka hoʻokumu ʻana o ka hoʻokumu ʻana, hiki ke hoʻokō ʻia kahi mea maikaʻi loa ma ka hoʻohui ʻana i nā derivatives protein a i ʻole amphoterics.